Custom-made knee prosthesis
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A technological breakthrough in
total knee replacement

Based on revolutionary technology, the ORIGIN® prosthesis is a major breakthrough aimed at improving patient satisfaction and enabling a more efficient surgical procedure.



to reproduce alignment and kinematics

Every patient is unique

Constitutional morphology varies greatly from one individual to another in the general population, whether healthy or not. The work of Professor Hirschmann (1) has highlighted the very wide variation in the constitutional forms of the femur and tibia independently of each other, and independently of the alignment of the lower limb. These variations influence the functional parameters of both.


Reproduce the constitutional morphotype

Because each individual is different, the ORIGIN® prosthesis is designed to reproduce the constitutional morphotype (or functional phenotype) of each patient anatomically:

  • Reproduction of lower limb alignment (HKA);
  • Restoration of joint space directly by customizing the offset of the prosthetic condyles.

Reproduce the radii of curvature

The sagittal anatomical profile varies from patient to patient. The ORIGIN® prosthesis enables accurate reproduction of the radii (J-curve) in a personalised manner:

  • Customization of the femur and insert radii;
  • Reproduction of the patient’s natural kinematics;
  • Optimal coverage of the posterior condyles.

No compromise on alignment

The ORIGIN® prosthesis is designed to allow axial alignment of the tibial base independent of the overlapping bone contour. There is no need to compromise between the two (2).


to replicate bone contours

No compromise on form

The ORIGIN® prosthesis is designed to adapt perfectly to the anatomical contours of each individual to enable strict resurfacing of the resected bone surfaces:

  • No prosthetic overhangs to avoid conflict with soft tissue and to avoid limiting mobility in flexion;
  • No bone under-covering to increase the stability of the femur on the tibia, limit bleeding and maximize the support of the tibial base on the cortical bone;
  • No size compromise between medial-lateral and anterior-posterior dimensions.

Natural patellar tracking

Thanks to the customization of the prosthetic trochlea, the ORIGIN® prosthesis is designed to restore natural patellar tracking for each patient, and offers the possibility of resurfacing the patella by means of an anatomical medialized dome patellar component.

Minimal bone resections

The customization of the ORIGIN® prosthesis design also takes into account the patient’s size to adapt the bone resections proportionally. Thus, a small patient will benefit from significantly less prosthetic space than a large patient, in order to preserve as much of his or her bone capital as possible.

Avoiding bone conflicts

The position of the tibial keel is also customized to avoid any risk of conflict with the cortical bone during final implantation.

More natural stability

By restoring each patient’s condylar spacing, the ORIGIN® prosthesis is designed to increase the intrinsic stability of the femur on the tibia and to facilitate more natural kinematics during flexion.


for precise positioning

Precise positioning of implants

With KNEE-PLAN® custom-made guides, the surgeon benefits from a tool that combines high technology and ease of use to make cuts and position implants with precision:

  • Simple positioning and stability of the custom-made guides ensured by osteophyte-based supports;
  • Cutting directly on the guides;
  • Higher precision than standard instrumentation for implant positioning (3).

Preoperative planning

The planning report is delivered with the ORIGIN® product and helps guide the surgeon throughout the procedure:

  • A reminder of the preoperative analysis and realignment strategy for each patient;
  • Numerous checks available to verify the positioning of the guides before making the cuts


for greater efficiency

Simplification of material

Because the implants and instruments are custom-made, the material required for the installation of an ORIGIN® prosthesis is reduced to the absolute essentials:

  • No more hospitalization for implants;
  • Custom-made and single-use instruments;
  • Only one basket of reusable instruments.

Maximize the efficiency of the procedure

The ORIGIN® model breaks with the orthopedic logistic model as it has existed for decades. The productivity of the medical team is maximized and the hospital can reduce its operating costs for each procedure:

  • Reduced instrument preparation time;
  • Fewer surgical steps to perform surgery, which significantly reduces operating time;
  • Reduced instrument processing costs (cleaning, sterilization, storage and maintenance).

Resources to download

(1) Bonnin M P, Beckers L, Leon A, Chauveau J, Müller J H, Tibesku C O, Aït-Si-Selmi T. Custom total knee arthroplasty facilitates restoration of constitutional coronal alignment.
Knee Surg Sports Traumatol Arthrosc. 2020 Jul 17.

(2) Hirschmann M T, Moser L B, Amsler F, Behrend H, Leclercq V, Hess S. Functional knee phenotypes: a novel classification for phenotyping the coronal lower limb alignment based on the native alignment in young non-osteoarthritic patients. Knee Surg Sports Traumatol Arthrosc. 2019 May;27(5):1394-1402.

(3) Moser L B, Hess S, Amsler F, Behrend H, Hirschmann M T. Native non-osteoarthritic knees have a highly variable coronal alignment: a systematic review. Knee Surg Sports Traumatol Arthrosc. 2019 May;27(5):1359-1367.

(4) Hirschmann M T, Hess S, Behrend H, Amsler F, Leclercq V, Moser L B. Phenotyping of hip-knee-ankle angle in young non-osteoarthritic knees provides better understanding of native alignment variability. Knee Surg Sports Traumatol Arthrosc. 2019 May;27(5):1378-1384.

(5) Hirschmann M T, Moser L B, Amsler F, Behrend H, Leclercq V, Hess S. Phenotyping the knee in young non-osteoarthritic knees shows a wide distribution of femoral and tibial coronal alignment. Knee Surg Sports Traumatol Arthrosc. 2019 May;27(5):1385-1393.

(6) Hess S, Moser L B, Amsler F, Behrend H, Hirschmann M T. Highly variable coronal tibial and femoral alignment in osteoarthritic knees: a systematic review. Knee Surg Sports Traumatol Arthrosc. 2019 May;27(5):1368-1377.

(7) Hirschmann M T, Behrend H. Functional knee phenotypes: a call for a more personalised and individualised approach to total knee arthroplasty? Knee Surg Sports Traumatol Arthrosc. 2018 Oct;26(10):2873-2874.

(8) Lampart M, Behrend H, Moser LB, Hirschmann M T. Due to great variability fixed HKS angle for alignment of the distal cut leads to a significant error in coronal TKA orientation. Knee Surg Sports Traumatol Arthrosc. 2019 May;27(5):1434-1441.

(9) Hochreiter B, Hirschmann M T, Amsler F, Behrend H. Highly variable tibial tubercle-trochlear groove distance (TT-TG) in osteoarthritic knees should be considered when performing TKA. Knee Surg Sports Traumatol Arthrosc. 2019 May;27(5):1403-1409.

(10) Bonnin M P, Saffarini M, Shepherd D, Bossard N, Dantony E. Oversizing the tibial component in TKAs: incidence, consequences and risk factors. Knee Surg Sports Traumatol Arthrosc. 2016 Aug;24(8):2532-40.

(11) Bonnin M P, Saffarini M, Bossard N, Dantony E, Victor J. Morphometric analysis of the distal femur in total knee arthroplasty and native knees. Bone Joint J. 2016 Jan;98-B(1):49-57.

(12) Bonnin M P, Schmidt A, Basiglini L, Bossard N, Dantony E. Mediolateral oversizing influences pain, function, and flexion after TKA. Knee Surg Sports Traumatol Arthrosc. 2013 Oct;21(10):2314-24.

(13) Bonnin M P, De Kok A, Verstraete M, Van Hoof T, Van Der Straten C, Saffarini M, Victor J. Popliteus impingement after TKA may occur with well-sized prostheses. Knee Surg Sports Traumatol Arthrosc. 2017 Jun;25(6):1720-1730.

(14) Bellemans J, Colyn W, Vandenneucker H, Victor J. The Chitranjan Ranawat award: is neutral mechanical alignment normal for all patients? The concept of constitutional varus. Clin Orthop Relat Res. 2012 Jan;470(1):45-53.

(15) Franceschi JP, Sbihi A, Computer Assisted Orthopedic Surgery Society – France (CAOS – France). 3D templating and patient-specific cutting guides (Knee-Plan) in total knee arthroplasty: postoperative CT-based assessment of implant positioning. Orthop Traumatol Surg Res. 2014 Oct;100(6 Suppl):S281-6.

(16) Sariali E. Kajetanek C, Catonné Y. Comparison of custom cutting guides based on three-dimensional computerized CT-scan planning and a conventional ancillary system based on two-dimensional planning in total knee arthroplasty: a randomized controlled trial. Int Orthop. 2019 Nov;43(11):2529-2538.

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